International Conference Of
Alternatives to Animal Experimentation

Portugal, 8th, 9th May, 2015

PROGRAMME

8TH MAY 2015

09h00 - 10h00 Registration

10h00 - 10h30 Opening Session
Dr. Duarte Cordeiro (Lisbon City Council)
Dr. Álvaro Mendonça (DGAV - Portuguese National Authority for Animal Health)
Dr.Laurentina Pedroso (Portuguese Veterinary Order)


SESSION 1 - Animal Experimentation: Past and Future

10h30 - 11h30 Keynote Lecture - Medical Research Beyond Invasive Animal Studies: A Paradigm Shift in Clinical Trials
Dr. Philip Low

11h30 - 12h00 Field and lab behavioural studies: an ethical approach
Dr. Luis Vicente

12h00 - 12h30 Humanising drug safety testing - a pragmatic validation study
Dr. Robert Coleman

12h30 - 13h00 Open Debate

13h00 - 14h30 Lunch Break


SESSION 2 - The Emergence of Alternatives - in vitro Technology

14h30 - 15h00 The NOTOX Project - The Challenge of in vitro to in vivo Extrapolation
Dr. Elmar Heinzle

15h00 - 15h30 In vitro approaches for detection of chemical sensitization
Dr. Teresa Rosete

15h30 - 16h00 In vitro methods and strategies for serious eye damage/eye irritation
Dr. João Barroso

16h00 - 16h30 Reconstructed human 3-dimensional skin models for testing phototoxic potential of ingredients and dermal formulations
Dr. Helena Kandarova

16h30 - 17h00 Targeting the stem cell population in chronic myeloid leukaemia
Dr. Helen Wheadon

17h00 - 18h30 Coffee Break and Poster Sessions

20h00 Conference Dinner


9TH MAY 2015

SESSION 3 - The new paths of Europe, for Citizenship and Ethics

10h00 - 11h00 Keynote Lecture - Bridging the gap between scientific progress in toxicology and the acceptance of 3R models for regulatory purposes
Dr. Bas Blaauboer

11h00 - 11h30 Portuguese legislation on the use of animals for scientific purposes
Dr. Ana Paula Martins

11h30 - 12h00 Nonanimal Testing: It’s Within REACH
Dr. Gilly Stoddart

12h00 - 12h30 Ethics Committee's review process in the implementation of the 3Rs
Dr. Manuel Rebelo

12h30 - 13h00 Open Debate

13h00 - 14h30 Lunch Break


SESSION 4 - The Emergence Of Alternatives - in silico Models

14h30 - 15h00 In Silico approaches to predict organ level toxicity: findings of the COSMOS Project
Dr. Mark Cronin

15h00 - 15h30 Re-thinking drug design: In-Silico, systems pharmacology approach to study the effect of statins on the early stage of atherosclerosis in humans
Dr. Vanessa Diaz

15h30 - 16h00 Genome-scale constraint-based modeling in biomedical research
Dr. Miguel Rocha

16h00 - 16h30 Coffee break and Poster Sessions


SESSION 5 - Clinical Research

16h30 - 17h00Defining the clinical research question: unnecessary repetition of animal studies - the case of fetal monitoring
Dr. Diogo Ayres-de-Campos

17h00 - 17h30 ADHD: what have we learned from clinical research and animal studies?
Dr. Constança Carvalho